Radford offers a notably affordable cost of living relative to much of Virginia. Rental prices for student apartments and shared houses are generally lower than in larger college towns, and everyday expenses like groceries and dining out are comparably modest.

The area around Radford University's campus and along East Main Street is quite walkable, with housing, dining, and amenities within easy reach on foot. Areas farther from campus are more car-dependent, as is common in small Virginia cities.

Radford is approximately 8 miles from Blacksburg, home to Virginia Tech. The drive typically takes about 15 minutes, making it feasible for Radford students to occasionally visit Blacksburg for dining, events, or shopping.

Radford's location in the New River Valley provides easy access to the New River for kayaking, tubing, and fishing, as well as hiking trails and Bisset Park. The region is well regarded among outdoor recreation enthusiasts in southwestern Virginia.

Radford is generally considered a safe college community with a relatively low crime rate for a small Virginia city. Students should follow standard precautions, particularly in less populated areas at night, and consult university safety resources for current guidance.